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Chicken Alfredo Lasagna

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BakedBreeBy BakedBreeJump to Recipe

Are you looking for an easy, healthy, wow the family kind of meal, that you can make ahead of time and whip out for a weeknight dinner? Then look no further than this delicious, tantalizing Chicken Alfredo Lasagna that will be sure to get you high marks on your culinary skills report card.

Creamy spinach and cheese lasagna baked to golden perfection, easy homemade Italian comfort food.

Old school cooking merged with modern day convenience, this unique lasagna recipe includes the tried-and-true perfection of grandma’s, traditional Italian cuisine, with today’s easy to prepare, mouthwatering ingredients. Perfectly marrying the past with the present, this one dish family dinner, contains all of the stellar food groups; carbohydrates, protein, dairy and vegetables. And the best part, you can prepare it far in advance, freeze it and it will be ready whenever you are.

Oozing with creamy goodness, the trio of cheeses united with the tender tendrils of spinach and the juiciness of the cooked to perfection chicken, all held together by a bed of lasagna noodles will satisfy even the most discerning of palates. It has it all in one bite. Salty, savory, full bodied tastes that come together perfectly to create a tantalizing entre that will elevate any dinner table, while at the same time keeping preparations simple and sublime. This dish will easily become a family favorite that will help you to create lasting dinner table memories for years to come.

Cooked chicken, shredded cheese, spinach, onions, garlic, sour cream, and baking ingredients for baked chicken casserole.

Why Chicken Alfredo Lasagna

The best part about this recipe is its ability to easily be customized to your own unique taste preferences. If you want it to be super cheesy, add more cheese, or sneak in an additional kind of cheese. Or if making it “healthier” is your goal, cut back on the fat percentages in the cheeses, and/or add more vegetables to the mix. Make it your own unique creation, using the base recipe as your guide. Remember, our grandmothers and great grandmothers didn’t have recipe books or google. They just cooked by taste and memory.

Cream cheese and spinach mixture for baked dishes in a skillet.

How to Make Ahead and Store?

The beauty of this particular dish is how easy it is to make ahead and store. All you have to do is follow the directions through step number six, then cover with aluminum foil. It will stay in a refrigerator up to 24 hours. Or it can be constructed in a disposable aluminum baking dish, covered with aluminum foil and frozen for up to three months.

How to make sure the Alfredo sauce does not brown?

Be careful to add the milk and cream, just a little at a time, whisk constantly. Then add in the cheese and keep whisking until there are no lumps and the cheese is fully melted.

Creamy chicken and spinach lasagna slice on a rustic plate, highlighting comfort food recipes.

Serving Suggestions

Although this recipe will awe your family and dinner guests all by itself, you can elevate the eating experience by pairing it with some appetizing garlic breadsticks or cheddar bay biscuits. If you are looking for something on the lighter side, perhaps try a simple side salad made of greens and vegetables, or some hearty roasted garlic drizzled with just a hint of butter. The choice is yours! Enjoy!

Creamy spinach and chicken lasagna with melted cheese, baked to perfection, from Baked Bree.
Creamy spinach and cheese lasagna baked to golden perfection, easy homemade Italian comfort food.

Chicken Alfredo Lasagna

Soft baked bread with golden crust on a rustic wooden board, perfect for breakfast or sandwiches.BakedBree
No ratings yet
Print Recipe Pin Recipe
Prep Time 25 minutes mins
Cook Time 40 minutes mins
Resting Time 10 minutes mins
Total Time 1 hour hr 15 minutes mins
Course dinner
Cuisine American, Italian
Servings 16
Calories 497 kcal

Ingredients
  

  • 2 tablespoons unsalted butter
  • 2 garlic cloves minced
  • 1 cup onion finely chopped
  • 10 ounces fresh baby spinach
  • 4 cups heavy cream
  • 1 1/2 cups grated Parmesan cheese
  • 15 ounces ricotta cheese whole milk preferred
  • 1/4 teaspoon black pepper freshly ground
  • 1 1/2 teaspoons salt
  • 3 cups shredded rotisserie chicken skin removed
  • 15 lasagna noodles cooked al dente
  • 3 cups shredded mozzarella cheese

Instructions
 

  • Begin by preheating your oven to 350°F. This ensures your lasagna will cook evenly.
  • Melt the butter in a large skillet over medium-high heat. Add the minced garlic and chopped onion, cooking until the onion is soft (3-5 minutes).
    Sautéed onions and garlic in a cast iron skillet.
  • Add the fresh baby spinach to the skillet, stirring until it wilts down.
    Fresh sautéed spinach with garlic in a black skillet, on white background.
  • Pour in the heavy cream, and stir in the grated Parmesan cheese, ricotta cheese, black pepper, and salt. Add the shredded chicken last. Let the mixture come to a simmer, then remove from heat.
    Cream cheese and spinach mixture for baked dishes in a skillet.
  • In a 9×13 inch deep baking dish, spread a spoonful of the Alfredo mixture on the bottom. Place about 5 lasagna noodles over the sauce, slightly overlapping.
    Creamy cheese and herb layered casserole in a glass baking dish, ready to bake.
  • Spoon a generous amount of the chicken Alfredo mixture over the noodles, spreading it evenly. Sprinkle a third of the shredded mozzarella cheese on top.
    Creamy homemade casserole with shredded cheese, ready to bake, from Baked Bree.
  • Continue layering with noodles, Alfredo mixture, and mozzarella cheese until all ingredients are used, finishing with a layer of cheese on top for the crust.
    Creamy vegetable casserole with shredded cheese and herbs.
  • Cover with foil and bake for about 35 minutes.
    Baked Bree - Aluminum foil-wrapped baking dish for easy oven roasting or baking.
  • Remove the foil and broil for an additional 2-3 minutes.
    Creamy spinach and mushroom casserole baked with melted cheese in a white baking dish.
  • Let the lasagna sit for about 10 minutes before slicing.

Nutrition

Calories: 497kcalCarbohydrates: 25gProtein: 20gFat: 35gSaturated Fat: 21gSodium: 656mgFiber: 1g
Keyword Chicken Alfredo Lasagna
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Published: Apr 3, 2024 | Updated: Feb 17, 2026

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