In a bowl, combine sliced strawberries and granulated sugar. Let sit for 20 minutes to macerate.
In a separate bowl, whisk together mascarpone cheese, heavy whipping cream, powdered sugar, and vanilla extract until the mixture forms stiff peaks.
Dip ladyfingers quickly into a mixture of water and orange juice, then line the bottom of an 8x8 inch dish with half of the ladyfingers.
Spread half of the mascarpone mixture over the ladyfingers.
Arrange half of the macerated strawberries on top of the mascarpone layer.
Repeat the layers with the remaining ladyfingers, mascarpone mixture, and strawberries.
Cover and refrigerate for at least 3 hours, or until set.
Garnish with additional sliced strawberries before serving.