Preheat your oven to 350°F and lightly grease a 8x4-inch loaf pan.

Combine the salmon, crushed crackers, milk, beaten eggs, melted butter, salt, pepper, minced onion, parsley, lemon juice, and garlic powder in a large bowl. Stir until all ingredients are well mixed.

Transfer the mixture to the prepared loaf pan and gently press it down. Bake for 35-45 minutes, or until the top is lightly browned and a knife inserted in the center comes out clean.

Let stand for 5-10 minutes before slicing and serving with lemon wedges.