Pat the pickle slices dry with paper towels.
Combine the flour, garlic powder, paprika, salt, and black pepper in a shallow dish.
In another bowl, beat the egg, milk, and Worcestershire sauce together.
Heat about 1 inch of vegetable oil in a deep skillet or pot to 375°F.
Dunk the pickle slices into the flour mixture, shaking off any excess.
Dip the floured pickles into the egg mixture.
Dredge the pickles once more in the flour mixture.
Carefully place the coated pickles into the hot oil, frying in batches to avoid overcrowding.
Fry for 2 to 3 minutes or until golden brown, turning once.
Remove the pickles with a slotted spoon and place on paper towels to drain.