In a large bowl, combine the chicken thighs with olive oil, salt, black pepper, garlic powder, onion powder, smoked paprika, ground cumin, and cayenne pepper. Mix well.
Place the seasoned chicken thighs in a single layer on a rimmed baking sheet.
Bake in the preheated oven for about 30 minutes or until the internal temperature reaches 165°F.
Remove from the oven and let rest for a few minutes before serving.